Role of Mirtazapine in Ameliorating Sleep Disordered Breathing
Status:
Completed
Trial end date:
2019-05-18
Target enrollment:
Participant gender:
Summary
The purpose of this study is to look at the effect of using Mirtazapine to target a specific
pathway in the body, that relies on a natural chemical the body produces called 'serotonin',
in patients with spinal cord injury (SCI) and non-injured persons during sleep. During this
part of the study participants will be asked to take Mirtazapine (15mg per day) and a placebo
in a random fashion, each for a one week period (drug period) of time followed by one week
without drugs (washout period). The drugs will not be taken all at the same time, but each
will be taken separately for one weeks followed by a night study to look at the effect the
Mirtazapine/placebo pill has on the way the body responds during sleep.