Role of Calcium And Vitamin D In Nutritional Rickets And It's Management
Status:
Completed
Trial end date:
2009-04-01
Target enrollment:
Participant gender:
Summary
Rickets, a common nutritional disorder, is usually considered to be due to vitamin D
deficiency. However, in the last few decades many studies have shown that in tropical
countries, with abundance of sunshine, calcium deficiency may play a more important role in
the causation of rickets. Studies from adults in India have also shown that calcium intake of
our population is much below the recommended allowance. The calcium deficiency gets
compounded by the high level of phytates in the conventional vegetarian diet consumed by the
majority of the population. There are few studies on children in India / other Asian
countries on assessment of dietary calcium intake.
However, recent studies from many nations of the world have also shown a wide spread
prevalence of vitamin D deficiency in adolescent and adult population. A study done at our
own hospital has shown a high prevalence of vitamin D deficiency in lactating mothers and
their infants.
Since both Calcium and Vitamin D deficiency are likely to be present in children, it is not
clear what plays a more important role in the etiology of rickets in India or other Asian
countries.
The present study is therefore planned with the following objectives:
1. To study the dietary calcium intake, sun exposure and serum vitamin D levels in children
with and without rickets.
2. To compare the role of Calcium Carbonate, Vitamin D and a combination of the two in the
treatment of nutritional rickets.
Phase:
Phase 4
Details
Lead Sponsor:
Lady Hardinge Medical College
Treatments:
Calcium Calcium Carbonate Calcium, Dietary Ergocalciferols Vitamin D Vitamins