Role of Antibiotics to Reduce Infectious Complications in Tube Thoracotomy Management of Traumatic Hemopneumothorax

• Status: Completed
• Trial end date: 2009-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to examine the efficacy of prophylactic antibiotics in patients with chest tubes for management of thoracic injuries in the reduction of the incidence of empyema as compared to placebo.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: St. Luke's Hospital, Pennsylvania
• Treatments: Anti-Bacterial Agents; Antibiotics, Antitubercular; Cefazolin; Clindamycin; Clindamycin palmitate; Clindamycin phosphate

Criteria

Inclusion Criteria:

1. Age ≥ 16 years of age.

2. Admission to Trauma, General Surgery, and/or Surgical Critical Care services.

3. Traumatic pneumothorax, hemothorax or hemopneumothorax

Exclusion Criteria:

1. Pregnancy

2. Open fracture

3. Immunocompromised

4. Require antibiotics for treatment of other injuries

5. Chest tube placement greater than 72hrs after admission