Repetitive transcranial magnetic stimulation (rTMS) uses a magnetic field to non-invasively
induce electrical function within the brain. Stimulation allows brain cells to change the way
that they adapt and communicate with each other, known as 'synaptic plasticity'. It is
thought that alterations in these adaptive brain changes underlie the ability of rTMS to
treat mental illnesses like depression. rTMS is a Health Canada approved treatment for
depression, however, 2/3rds of people fail to show meaningful improvement. This highlights
the need for more effective therapeutic means. The purpose of the present study is to augment
the therapeutic abilities of rTMS through the conjunctive use of a medication that also
increases synaptic plasticity. We will pair TMS with an electroencephalograph (EEG) to
measure activity dependent changes in the frontal cortex following rTMS.