Overview

Rituximab and Belimumab Combination Therapy in PR3 Vasculitis

Status:
Recruiting
Trial end date:
2023-02-01
Target enrollment:
Participant gender:
Summary
Mechanistic study to assess whether dual B-cell immunotherapy by co-administration of rituximab and belimumab will result in improvements in biological endpoints, functional outcomes and clinical status compared to rituximab with placebo.
Phase:
Phase 2
Details
Lead Sponsor:
Rachel Jones
Collaborators:
GlaxoSmithKline
Imperial College London
Medical Research Council
Newcastle University
University College, London
University of Cambridge
University of Glasgow
Treatments:
Belimumab
Prednisolone
Prednisone
Rituximab