Ritodrine in Oral Maintenance of Tocolysis After Active Preterm Labor

• Status: Completed
• Trial end date: 2005-08-01
• Target enrollment: 0
• Participant gender: Female

Summary

This is a trial comparing the efficacy of oral ritodrine in the form of sustained release capsules for the maintenance of uterine quiescence after successfully treated episode of threatened preterm labor.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Zagreb
• Collaborator: Ministry of Science, Education and Sport, Republic of Croatia
• Treatments: Ritodrine

Criteria

Inclusion Criteria:

• Pregnancy between completed 24 to 24 weeks

• Successfully treated episode of threatened preterm labour by intravenous preparations

• No uterine contractions

Exclusion Criteria:

• Uterine contractions (painful, clinically palpable, or present on cardiotocography)

• Cervical dilatation of ≥5 cm

• Clinical and laboratory signs of infection defined as offensive vaginal discharge on clinical examination, vaginal pH ≥5, white blood cell (WBC) count >16×109/L, and C-reactive protein (CRP) >10 mg/L

• Positive findings of microorganisms rather than normal vaginal flora on high vaginal swab

• Any signs of fetal distress according to cardiotocography, Doppler assessment of blood flow in umbilical artery, and biophysical profile of <8.