Risperidone vs. Paroxetine for Panic Attacks

• Status: Terminated
• Trial end date: 2005-07-01
• Target enrollment: 0
• Participant gender: All

Summary

We are comparing the efficacy of Risperidone versus Paroxetine in the treatment of panic symptoms. The study hypothesis is that Risperidone will be a superior medicine for treating panic.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Beth Israel Medical Center
• Treatments: Paroxetine; Risperidone

Criteria

Inclusion Criteria:

• Males and females, ages 21-55.

• Ability to sign an informed consent

• Diagnosis of Panic Disorder, or MDD with Panic attacks, single episode, recurrent, or chronic

• HAM-A score >17

Exclusion Criteria:

• Alcohol or substance abuse within the last 6 months

• Current diagnosis of Obsessive-Compulsive Disorder

• Current diagnosis of Schizophrenia, Schizoaffective Disorder, or Bipolar Mood Disorder

• Use of antipsychotic medications over the two months preceding enrollment in the study

• Changes in antidepressant or mood stabilizer dosing over the two months preceding enrollment in the study

• Previous adverse reaction to risperidone or paroxetine.