Overview

Rintatolimod and IFN Alpha-2b for the Treatment of COVID-19 in Cancer Patients

Status:
Recruiting
Trial end date:
2022-11-17
Target enrollment:
Participant gender:
Summary
This phase I/IIa trial studies the best dose and side effects of rintatolimod and interferon (IFN) alpha-2b in treating cancer patients with COVID-19 infection. Interferon alpha is a protein important for defense against viruses. It activates immune responses that help to clear viral infection. Rintatolimod is double stranded ribonucleic acid (RNA) designed to mimic viral infection by stimulating immune pathways that are normally activated during viral infection. Giving rintatolimod and interferon alpha-2b may activate the immune system to limit the replication and spread of the virus.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Roswell Park Cancer Institute
Collaborator:
National Cancer Institute (NCI)
Treatments:
Interferon alpha-2
Interferon-alpha
Interferons
poly(I).poly(c12,U)