It is important for women taking rifampin to be aware if they are at greater risk of an
unintended pregnancy while on the implant. An unintended pregnancy has many social,
emotional, and financial impacts on women and society. Rifampin is also a Class C medication
for pregnancy and could have potential negative effects on a developing fetus. Additionally,
women considering rifampin for treatment of LTBI face additional risks with an unintended
pregnancy, making the reliability of contraception even more important for these women. The
results of this study can directly inform counseling on a national and international basis
for women who use the contraceptive implant and are considering their treatment options for
LTBI.