Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose)

• Status: NOT_YET_RECRUITING
• Trial end date: 2033-03-01

Summary

To find out if adding medication can help treat or prevent lymphedema and/or fibrosis related to radiation therapy, in survivors of head and neck cancer. Researchers will compare these drugs to find the most effective therapy for preventing or limiting these side effects.

• Phase: PHASE2

Details

• Lead Sponsor: M.D. Anderson Cancer Center
• Treatments: Ketoprofen; Pentoxifylline; Pharmaceutical Preparations; Pravastatin; Standard of Care; Tocopherols