Overview

Reversal of Hepatic Impairment in Patients With Hepatitis C Virus (HCV) and Early Decompensation of Cirrhosis

Status:
Terminated
Trial end date:
2016-07-18
Target enrollment:
Participant gender:
Summary
1. Achieve sustained virologic response (SVR) in patients infected with HCV genotype 1, cirrhosis, and early clinical decompensation using 12 weeks of Olysio/Sovaldi/Ribavirin (or known as: Simeprevir(SMV)/Sofosbuvir(SOF)/Ribavirin (RBV). 2. Hepatic improvement during and after Simeprevir(SMV)/Sofosbuvir(SOF)/Ribavirin(RBV) treatment using a new test of liver function, HepQuant-SHUNT.
Phase:
Phase 3
Details
Lead Sponsor:
University of Colorado, Denver
Collaborator:
Janssen Scientific Affairs, LLC
Treatments:
Ribavirin
Sofosbuvir