Retrospective Study of the Effectiveness and Safety of Niacin and Steroid Eye Drops for Retinal Vein Occlusions
Status:
Terminated
Trial end date:
2016-10-01
Target enrollment:
Participant gender:
Summary
The aim of this study is to develop a less risky, yet effective and more sustainable
treatment for retinal vein occlusions than the current commonly used approach of repeated
intravitreal triamcinolone acetonide (Kenalog) injections. The types of retinal vien
occlusion that are being studied include central (CVRO), hemi-retinal (HRVO),and branch
(BRVO) retinal vein occlusion. Niacin, (Nicotinic Acid, not Nicotinamide) a B-vitamin, has
lipid lowering and vasodilating properties. The combination of Niacin and Prednisolone
Acetate steroid eye drops as a non-invasive treatment approach was developed by the Principal
Investigator. The Niacin dilates the retinal vessels, hopefully encouraging earlier
collateral vessel formation aimed at bypassing the venous obstruction, thus restoring venous
outflow. The Prednisolone Acetate steroid eye drops are aimed at reducing vascular leakage
and therefore the macular edema in the eye while the Niacin is taking effect.