Retinal Blood Flow and Microthrombi in Type 1 Diabetes
Status:
Completed
Trial end date:
2006-03-01
Target enrollment:
Participant gender:
Summary
The project aims to find mechanisms for the abnormal retinal blood flow that in diabetic
patients often precedes any evidence of clinical retinopathy and may contribute to the
development of retinopathy.
Specifically, the projects tests the hypothesis that reduced retinal blood flow found in
young patients with type 1 diabetes reflects increased resistance in the small vessels of the
retina caused by the formation of small blood clots, called microthrombi; and that
antiplatelet agents normalize the reduced retinal blood flow.