Research Evaluating the Value of Augmenting Medication With Psychotherapy

• Status: Completed
• Trial end date: 2007-03-01
• Target enrollment: 0
• Participant gender: All

Summary

This 24-week study, with a 12-month follow up period, will compare the effectiveness of antidepressant medication alone to the combination of psychotherapy and antidepressant medication in patients with chronic depression.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Weill Medical College of Cornell University
• Collaborator: National Institute of Mental Health (NIMH)
• Treatments: Antidepressive Agents

Criteria

Inclusion Criteria

• Major depressive episode

• Depressive symptoms > 2 years without remission

• Hamilton Depression Scale (HAM-D) score > 20

• Fluent in English

Exclusion Criteria

• Psychotic disorders, bipolar disorder, post traumatic stress disorder, obsessive compulsive disorder, or eating disorder

• Serious, unstable, or terminal medical condition

• Axis II diagnosis of antisocial, schizotypal, or severe borderline personality disorder

• Previous treatment with CBASP

• Previous ineffective treatment with 4 of the medication treatments used in the study

• Substance abuse

• Pregnancy

• Not willing to end other psychiatric treatment