Rescue Endovascular Therapy for Progressive Acute Mild Ischemic Stroke With Large Vascular Occlusion
Status:
Recruiting
Trial end date:
2026-03-30
Target enrollment:
Participant gender:
Summary
Endovascular therapy (EVT) added on best medical management is currently recommended in acute
large vascular occlusion (LVO) stroke patients with National Institutes of Health Stroke
Scale (NIHSS) score >5. Thus, a sizeable fraction of patients with a minor stroke that do not
undergo cerebrovascular screening may experience an early neurological deterioration (END)
due to LVO, possibly leading to poor long-term functional outcome. However, whether these
patients may still benefit from a rescue EVT is unknown, especially in a late window (>24
hours). In this study, the investigators assume that best medical management plus EVT might
be superior than best medical management alone in a late window for minor stroke patients who
have experienced an LVO and END. The primary objective of the study was to establish the
safety and efficacy of EVT in a late window for minor stroke patients in the anterior
circulation who experienced an LVO and END.
Phase:
N/A
Details
Lead Sponsor:
First Affiliated Hospital of Wannan Medical College
Collaborator:
The First Affiliated Hospital of Anhui Medical University