Repurposing Probenecid as a Positive Inotrope for the Treatment of Heart Failure
Status:
Completed
Trial end date:
2015-06-01
Target enrollment:
Participant gender:
Summary
Probenecid is an FDA approved drug for the treatment gout and hyperuricemia. It has been used
safely in humans for decades for this and other indications. The investigators have recently
discovered that this drug can also stimulate other receptors in the heart and therefore
improve its function. The hypothesis of this study is that probenecid can be used to improve
the function of the heart and therefore the symptoms in patients with heart failure.