Overview

Repurposing Metformin as a Leukemia-preventive Drug in CCUS and LR-MDS

Status:
Not yet recruiting
Trial end date:
2025-11-01
Target enrollment:
Participant gender:
Summary
This is a phase 2 single-arm pilot study of the efficacy and safety of metformin in patients with clonal cytopenia of undetermined significance (CCUS) or lower-risk myelodysplastic syndrome (MDS).
Phase:
Phase 2
Details
Lead Sponsor:
Kirsten Grønbæk
Collaborators:
Herlev Hospital
Region Hovedstadens Apotek
Rigshospitalet, Denmark
Steno Diabetes Center Copenhagen
Technical University of Denmark
University of Copenhagen
Van Andel Research Institute
Zealand University Hospital
Treatments:
Metformin