Reproductive Outcome of EM Treated by GnRH-a Associated With Laparoscopy

• Status: Unknown status
• Trial end date: 2021-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study is a multicenter, randomized-control-trial. This study select 1184 Infertile patients associated with endometriosis diagnosed by laparoscopy surgery. Patients are going to be divided into two groups according to 1:1 ratio randomly assigned to receive GnRH-a. Cumulative pregnancy rate, end of treatment to natural pregnancy time, accept the assisted reproductive treatment rate, miscarriage rate, live birth rate will be recorded.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Peking University People's Hospital
• Treatments: Goserelin

Criteria

Inclusion Criteria:

• Infertile patients

• Endometriosis I-II phase：according to Revised American Society for Reproductive Medicine classification of endometriosis: 1996

• BMI:19-28 kg/㎡

• Ovarian reserve function is normal（M2-5：bilateral antral follicles≥6 FSH：5-12U/ml）

Exclusion Criteria:

• Male factor causes infertility

• hydrosalpinx or salpingemphraxis

• Uterine malformation

• Uterine cavity lesion

• Contra-indications for GnRH-a

• not willing to participate