Repeat Ivermectin Mass Drug Administrations for Control of Malaria: a Pilot Safety and Efficacy Study

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether repeated ivermectin mass drug administrations to Burkinabé villagers, performed in three week intervals over the rainy-season, is well-tolerated and safe, and also effective in reducing local malaria transmission and thus clinical malaria episodes in treated village children.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Colorado State University
• Collaborators: Centre Muraz; Institut de Recherche en Sciences de la Sante, Burkina Faso; Ministère de la Santé du Burkina Faso
• Treatments: Albendazole; Ivermectin

Criteria

Inclusion Criteria:

• Residence in the study site

• Able to understand the information and willing to give consent and assent (parent or guardian consent if study participant age is < 18 years)

Exclusion Criteria:

• Residence outside of in the study site

• Height ≤ 90 cm

• Permanent disability, serious medical illness that prevents or impedes study participation and/or comprehension

• Pregnancy

• Breast feeding if infant is within 1 week of birth

• Known allergy to the study drugs