Reparixin in Prevention of Delayed Graft Function After Kidney Transplantation
Status:
Completed
Trial end date:
2008-06-01
Target enrollment:
Participant gender:
Summary
The chemokine CXCL8 plays a key role in the recruitment and activation of polymorphonuclear
neutrophils in post-ischemia reperfusion injury after solid organ transplantation. Reparixin
is a novel, specific inhibitor of CXCL8. This study is configured to explore the safety and
efficacy of reparixin in preventing the delayed graft function (DGF) after kidney
transplantation.