Renin-Guided Therapeutics in the Management of Untreated, Uncontrolled, or Complicated Hypertension
Status:
Completed
Trial end date:
2005-09-01
Target enrollment:
Participant gender:
Summary
Plasma renin values determine whether volume or vasoconstrictor (renin) factors predominate
in elevating blood pressure and are useful in selecting effective antihypertensive
therapy.2,3
The researchers hypothesize that:
1. Plasma renin-guided therapeutics will improve systolic and diastolic blood pressure
control in patients with untreated hypertension as well as in patients with treatment
refractory or resistant hypertension that are managed by Clinical Hypertension
Specialists.
2. Renin-guided therapeutics will reduce the number of medications required to maintain
blood pressure control to <140/90 mmHg in hypertensive patients receiving 3 or more
medications, while under the care of a Clinical Hypertension Specialist.
3. Renin-guided therapeutics selection will reduce the total cost of antihypertensive care
provided by Clinical Hypertension Specialists.
Phase:
N/A
Details
Lead Sponsor:
Medical University of South Carolina
Collaborator:
New York Presbyterian Hospital
Treatments:
Antihypertensive Agents Coal Tar Hydrochlorothiazide