Overview Renin-Angiotensin and Fibrinolysis in Humans: Effect of Long-Term PDE5 Inhibition on Glucose Homeostasis Status: Terminated Trial end date: 2016-11-01 Target enrollment: Participant gender: Summary The purpose of this study is to determine the effect of chronic PDE5 inhibitor therapy on glucose metabolism in persons with prediabetes. Phase: Phase 4 Details Lead Sponsor: Vanderbilt UniversityTreatments: Sildenafil Citrate