Overview

Renal Optimization Strategies Evaluation in Acute Heart Failure and Reliable Evaluation of Dyspnea in the Heart Failure Network (ROSE) Study

Status:
Completed

Trial end date:
2013-06-01

Target enrollment:

Participant gender:

Summary

The purpose of this study is to determine the benefits and safety of intravenous administration of low dose nesiritide or low dose dopamine in patients with congestive heart failure and kidney dysfunction. There is a substudy in a subset of subjects that is being used to determine whether the Provocative Dyspnea Severity Score (pDSS) is a more sensitive index of variability in clinical status than the dyspnea VAS assessed without standardization of conditions at assessments.

Phase:

Phase 2

Details

Lead Sponsor:

Duke University

Collaborator:

National Heart, Lung, and Blood Institute (NHLBI)

Treatments:

Dopamine
Dopamine Agents
Natriuretic Peptide, Brain