Remote Ischemic Conditioning for the Treatment of Intracerebral Hemorrhage
Status:
Recruiting
Trial end date:
2023-06-30
Target enrollment:
Participant gender:
Summary
Intracerebral hemorrhage (ICH) results from the rupture of small vessels damaged by chronic
hypertension, amyloid angiopathy or other disease. Currently, ICH has been a devastating type
of stroke that lacking effective therapy. Remote ischemic conditioning (RIC), a
systematically protective strategy, has been found to have neuroprotective effects by in
patients with ischemic stroke. In addition, animal studies show that RIC is safe in ICH model
and it could accelerate the absorption of hematoma. In a previous clinical study (RICH-1),
RIC have been found to be safe and well-tolerated in patients with ICH. Therefore, the
investigators plan to undertake this study to further evaluate the safety and efficacy of RIC
in patients with ICH.
The investigators hypothesize that treatment with RIC will accelerate the absorption of
hematoma and improve patients' functional outcomes. Results of this study can potentially
bring into account new means to improve the outcomes of ICH patients.