Remimazolam Total Intravenous Anesthesia Under Analgesia Nociception Index-guidance
Status:
Not yet recruiting
Trial end date:
2024-03-21
Target enrollment:
Participant gender:
Summary
We hypothesized that intraoperative opioid consumption would be different between remimazolam
and propofol if the ANI-guided remifentanil continuous infusion rate was adjusted when the
depth of anesthesia was maintained at similar depths with remimazolam or propofol under total
intravenous anesthesia. The purpose of this study is to compare the intraoperative
remifentanil requirement in patients undergoing total knee arthroplasty when the
intraoperative remifentanil dose adjustment was performed under the ANI guidance while
maintaining a similar depth of anesthesia with remimazolam or propofol.