Remimazolam Phase II Cardiac Anesthesia Study

• Status: Completed
• Trial end date: 2014-02-19
• Target enrollment: 0
• Participant gender: All

Summary

This phase II study in patients undergoing elective cardiac surgery will evaluate the efficacy, safety, and pharmacokinetics of remimazolam, compared with propofol and sevoflurane, during the induction and maintenance of general anesthesia.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Paion UK Ltd.
• Collaborator: Aptiv Solutions
• Treatments: Fentanyl; Propofol; Remifentanil; Rocuronium; Sevoflurane

Criteria

Inclusion Criteria:

• scheduled for major elective cardiac surgery.

• scheduled for mechanical ventilation via tracheal intubation.

Exclusion Criteria:

• thoraco-abdominal replacement of the aorta or other procedure expected to be accompanied by a massive hemorrhage (at least 15% of the circulating blood volume).