Remifentanil and Atropine for Intubation in Neonates

• Status: Completed
• Trial end date: 2008-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators hypothesize that the use of a combination of Atropine and Remifentanil will safely facilitate non emergent intubation procedure as effectively as the protocol of Atropine, Fentanyl, and Succinylcholine.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: King Saud University
• Collaborator: McMaster University
• Treatments: Atropine; Fentanyl; Remifentanil; Succinylcholine

Criteria

Inclusion Criteria:

• Hemodynamically stable neonates of any gestational age admitted to the Neonatal Intensive Care Unit at McMaster Children's Hospital requiring an elective endotracheal intubation was anticipated.

Exclusion Criteria:

• Urgent intubations

• Cyanotic congenital heart lesions

• Anticipated difficult airway

• Concurrent or recently administered (within 3 hours of the procedure) intravenous opioid infusions

• Pre-existing hyperkalemia

• Family history of malignant hyperthermia

• Prior enrollment