Remifentanil Requirement for Acceptable Intubating Condition
Status:
Completed
Trial end date:
2018-04-16
Target enrollment:
Participant gender:
Summary
Ketamine and opioid are known to improve the intubating condition, respectively. Combination
of ketamine and opioid potentiate analgesic effect and give hemodynamic stability in
complementary manner. Therefore, the combination use of ketamine and remifentanil could be
useful for acceptable intubating condition in the general anesthesia without the use of
neuromuscular blocking agent. Generally, induction dose of ketamine ranges between 1 and 2
mg. There was no report about the optimal dose of remifentanil with 1 or 2 mg ketamine
induction dose for intubation without neuromuscular blocking agent. The investigators focus
on remifentanil dose using Dixon's up and down method.