Remifentanil Infusion Alone During the Closure Period for Early Emergence Following Craniotomy

• Status: Completed
• Trial end date: 2015-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Total intravenous anaesthesia using propofol and remifentanil are routinely used drugs for this purpose. The hemodynamic stability and at the same time early emergency are the main goals following neurosurgery. However there is no standard for discontinuation time for manually controlled systems today.

The investigators aimed to study the effect of remifentanil infusion alone for early emergence and hemodynamic stability during the closure period in patients undergoing supratentorial craniotomy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yeditepe University Hospital
• Treatments: Propofol; Remifentanil

Criteria

Inclusion Criteria:

• American Society of Anaesthesiologist physical status I-II

• Glasgow Coma Scale score of 15 points

• Elective supratentorial craniotomy for tumor resection

• Supine position

Exclusion Criteria:

• Obese patient

• Brain tumor greater than 30 mm in diameter

• Postoperative cranial drainage

• Hypertension

• Diabetes mellitus

• Reoperation

• Pregnant

• Breast feeding

• Allergy to the study medications

• History of cranial radiotherapy

• Frontal bone flap

• Intraoperative neuromonitoring