Relative Contributions of Predictors of Hyperandrogenism in Older vs. Young Women With PCOS
Status:
Recruiting
Trial end date:
2023-12-01
Target enrollment:
Participant gender:
Summary
The objective of the study is to determine the relative contributions of four established
predictors of hyperandrogenism (luteinizing hormone [LH] secretion, ovarian response to
recombinant human chorionic gonadotropin [r-hCG] administration, adrenal response to
adrenocorticotropic hormone [ACTH] administration, and hyperinsulinemia) in older vs. young
women with Polycystic Ovary Syndrome (PCOS) in a cross-sectional, physiological study. The
investigators hypothesize that hyperinsulinemia is a stronger independent predictor of free
testosterone (T) in older reproductive aged (vs. young) women with PCOS.