Regular Use Effect of Inhaled Ipratropium Bromide on Airway Responsiveness to Methacholine in Well-controlled Asthma

• Status: Completed
• Trial end date: 2020-03-13
• Target enrollment: 0
• Participant gender: All

Summary

Study is looking at the development of tolerance to methacholine following regular use of ipratropium bromide in mild asthmatics.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Saskatchewan
• Treatments: Bromides; Ipratropium; Methacholine Chloride

Criteria

Inclusion Criteria:

• airway responsiveness to methacholine

• adequate baseline lung function

• no respiratory infection or exposure to stimuli that may alter response to methacholine within 4 weeks

Exclusion Criteria:

• pregnancy

• current smoker

• requirement for medications other than salbutamol that will interfere with airway response to methacholine