Regional Lung Imaging Using Hyperpolarized Xenon Gas
Status:
Recruiting
Trial end date:
2022-09-01
Target enrollment:
Participant gender:
Summary
The investigators aim to use hyperpolarized xenon gas magnetic resonance imaging (MRI) and
computed tomography to develop a new technique capable of objectively and quantitatively
describing regional and structural lung abnormality. Since this is a relatively novel
technique, the investigators first need to acquire imaging and clinical data from a group of
participants with normal lungs. The investigators hope to generate an "atlas" of normality,
which will form the foundation of future studies to compare with patients suffering from
chronic respiratory disease. The investigators also aim to validate the new technique in
terms of intra-subject reproducibility.
Phase:
Phase 1
Details
Lead Sponsor:
Oxford University Hospitals NHS Trust
Collaborators:
National Institute for Health Research, United Kingdom University of Sheffield