Regional Anesthesia in Total Hip and Knee Arthroplasty

• Status: Not yet recruiting
• Trial end date: 2021-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to test whether the use of Ropivacaine and Mepivacaine are better in terms of effectiveness, cost, and safety than Bupivacaine as regional anesthetics in elective hip or knee replacement surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ottawa Hospital Research Institute
• Treatments: Anesthetics; Anesthetics, Local; Bupivacaine; Mepivacaine; Ropivacaine

Criteria

Inclusion Criteria:

• Patients undergoing total hip or knee replacement

Exclusion Criteria:

• Study refusal

• Inability to provide consent

• Contra-indications to spinal anesthesia (refusal, infection, anti-coagulation, bleeding diathesis)

• Bilateral surgery

• Revision surgery

• Pre-exiting chronic pain or opioid consumption ≥ 30mg oxycodone or equivalent

• Pregnancy

• Not receiving preoperative adductor canal block for any reason

• Contra-indication to multimodal analgesia (acetaminophen or NSAIDs)

• Obstructive sleep apnea requiring extended PACU stay

• History of severe postoperative nausea and vomiting