Reduction of Postoperative Gastrointestinal Dysmotility Following Total Laparoscopic Hysterectomy.
Status:
Completed
Trial end date:
2020-05-05
Target enrollment:
Participant gender:
Summary
Return of bowel function is an integral component of postoperative recovery following
minimally invasive gynecologic surgery. To date, there is no standardized regimen to optimize
bowel motility postoperatively. Clinical practices vary in the medications prescribed to
facilitate this process, as well as what is considered the norm for return of flatus and time
to first bowel movement.
This study is a randomized control trial. The primary outcome of the study is to assess the
effect of a standardized postoperative bowel care regimen on return of bowel function by
assessing the time to first bowel movement; a secondary outcome is to assess the effect of
such a regimen on time to first flatus. The hypothesis is that the prescription of a
laxative, rather than a stool softener or no agent, will expedite the time to first bowel
movement and first flatus. Other secondary outcomes and endpoints are assessing narcotic use
measured in total oral morphine equivalents in the first five days postoperatively, as well
as the constipation score and the PAC-SYM questionnaire.
Phase:
Phase 4
Details
Lead Sponsor:
The Cleveland Clinic
Collaborators:
Jennifer Afton Cooper MD Katherine Smith MD Michael Sprague MD Pamela Frazzini-Padilla MD