Randomized controlled open-label non-inferiority trial comparing complete intravenous
antibiotic treatment with a short iv. course followed by oral antibiotics in neonates (0-28
days) with probable bacterial infection.
Primary outcome:
- Bacterial re-infection within 28 days after finishing of antibacterial therapy.
Secondary outcome(s):
- Pharmacokinetic profile of oral amoxicillin/clavulanic acid
- Quality of life
- Cost-effectiveness
- Alterations in gut microbiome
- Use of molecular techniques for better detection of bacterial pathogens