Reducing the Harmful Effects of Cannabis Use: Finding the Optimal CBD:THC Ratio
Status:
Completed
Trial end date:
2019-06-09
Target enrollment:
Participant gender:
Summary
This study will recruit healthy volunteers who use cannabis infrequently. Each participant
will attend the laboratory on five occasions: an initial visit to check that they are safe to
join the study and four days of testing.
Participants will be administered, in a randomized order, vaporized cannabis containing one
of four different ratios of CBD:THC (0:1, 1:1, 2:1, 3:1). The cannabis administration will
follow a standardised inhalation procedure using a medical-grade vaporizer device.
Participants will complete a series of tasks measuring cognition, psychosis, anxiety and
other subjective experiences.
The study will be carried out at the NIHR-Wellcome Trust Clinical Research Facility at King's
College Hospital.