Reducing Hypotensive Anesthesia Use With TXA During Orthognathic Surgery
Status:
Not yet recruiting
Trial end date:
2025-08-01
Target enrollment:
Participant gender:
Summary
This prospective study will analyze the need for deliberate hypotensive anesthesia (DHA)
during orthognathic surgery when tranexamic acid (TXA) is administered. DHA has been proven
to be effective although it comes with multiple risks related to organ hypoperfusion
including kidney injury, stroke, and cardiac ischemia. Therefore, it may be potentially safer
for patients to avoid deliberate hypotensive anesthesia if TXA alone adequately controls
blood loss and provides adequate surgical site visualization.