Reducing Delirium After Cardiac Surgery: A Multifaceted Approach Of Perioperative Care
Status:
Completed
Trial end date:
2015-04-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to reduce the incidence of postoperative delirium after
cardiac surgery in the elderly patient. This proposal is a clinical trial designed to reduce
delirium in patients undergoing cardiac surgery by replacing standard postoperative sedation
protocols (propofol, midazolam, opioids) with a new alpha2-adrenergic receptor agonist
(dexmedetomidine) possessing sedative, analgesic, and antinociceptive properties. Resource
utilization analysis will be performed to determine cost effectiveness of the new treatment
modality.
Phase:
N/A
Details
Lead Sponsor:
University Health Network, Toronto
Collaborators:
Hospira, Inc. Hospira, now a wholly owned subsidiary of Pfizer