Reduced Nicotine Content Cigarettes in Smokers of Lower Socioeconomic Status

• Status: Completed
• Trial end date: 2018-02-23
• Target enrollment: 0
• Participant gender: All

Summary

The overall goal of this study is to address the question of whether progressively lowering nicotine content in cigarettes can reduce or eliminate nicotine dependence in smokers of low socioeconomic status

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Milton S. Hershey Medical Center
• Collaborators: George Washington University; National Institute on Drug Abuse (NIDA)
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• Age 18-65

• Less than 16 years of education

• Able to understand, and sign consent

• Smoke >4 cigarettes/day for at least a year

• No quit attempt in prior 1 month and not planning to quit smoking within next 6 months

• Plan to live in local area for next 8 months

• Able to read and write in English

• Women not pregnant and taking steps to avoid pregnancy

Exclusion Criteria:

• College graduate

• Use of psychotropic drugs

• Significant medical condition, or immune system disorders, respiratory diseases, kidney or liver diseases or any other medical disorders that may affect biomarker data

• Use of any non-cigarette nicotine delivery product in the past week or smoking cessation medicine in prior 3 months

• Currently pregnant or nursing

• Uncontrolled serious psychotic illness or substance abuse

• History of difficulties providing blood samples-fainting, poor veins, anxiety