Reduced Contractile Reserve: a Therapeutic Target in Heart Failure With Preserved Ejection Fraction(HFpEF)
Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
Heart failure with preserved ejection fraction (HFpEF) accounts for over 50% of heart failure
cases in the United States, affecting a primarily elderly population. No treatment has been
shown to affect mortality in HFpEF, which is more than 50% at five years a hospitalization.
This project explores the underlying cardiovascular physiology of patients with HFpEF with
the goal of identifying new therapeutic targets that would allow improved treatment of this
devastating disease.