Reduce Cardiovascular Calcifications to Reduce QT Interval in Dialysis

• Status: Completed
• Trial end date: 2011-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Research proposal to evaluate the impact of different phosphate binders on the progression of cardiovascular calcification and QT dispersion in new haemodialysis patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Azienda Sanitaria ASL Avellino 2
• Treatments: Calcium; Calcium Carbonate; Calcium, Dietary; Sevelamer

Criteria

Inclusion Criteria:

• incident patients on haemodialysis (CKD stage 5);

• an informed consent will be provided at the study entry.

Exclusion Criteria:

• congenital prolongation of QT segment syndrome;

• QTc >440 ms; increased QTd;

• bradycardia <50 bpm;

• sintomatic arrhythmia or any other significant heart problems;

• electrolyte unbalances (especially hypokalemia, hypomagnesemia, hypocalcemia);

• abnormal liver function tests;

• hypothyroidism.