Red Yeast Rice in Subjects With Clinically Localized Prostate Cancer Undergoing Active Surveillance
Status:
Unknown status
Trial end date:
2017-12-01
Target enrollment:
Participant gender:
Summary
Agents that inhibit cholesterol synthesis are being investigated in cancers dependent upon
cholesterogenesis. Red yeast rice (RYR), is a reddish-purple fermented rice, containing
statins which are known to inhibit cholesterol synthesis. Laboratory studies have also shown
that RYR has direct effects on androgen dependent and androgen independent prostate cancer
cells, inhibiting their growth. It is thought that RYR may have clinical benefit in those
subjects with localized prostate cancer who have chosen to be managed by active surveillance.