Recurrent Wheezing in Infants: Risk Factors and Prevention With Probiotics.

• Status: Completed
• Trial end date: 2014-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate whether Probiotics promote reduction of recurrent wheezing in infants, stimulating the immune system to Th1 response.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Universidade Federal de Pernambuco
• Collaborator: Conselho Nacional de Desenvolvimento Científico e Tecnológico
• Treatments: Beclomethasone

Criteria

Inclusion Criteria:

• Infants aged six months to two years incomplete.

• Infants who have recurrent wheezing in the past 3 months.

• Infants under use of proper technique of inhaled corticosteroids: beclomethasone HFA spray - 50 mg - 2 times daily (100 mg / day) with spacer and face mask.

Exclusion Criteria:

• Patients who present congenital airway malformations, cystic fibrosis, chronic diseases in other systems, perinatal respiratory problems, allergy to the protein in cow's milk, intrathoracic tumors, Tuberculosis and Pulmonary Congenital immunodeficiencies, children who were premature: <37 weeks gestational age.

• Use of other products containing probiotics in its composition with previous exposure or even study period.

• Infant in use of anti-leukotrienes.

• Use recent antibiotic.