Rectal Dexmedetomidine Niosomes for Postoperative Analgesia in Pediatric Cancer Patients.

• Status: Not yet recruiting
• Trial end date: 2023-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Applying nanotechnology in drug delivery systems improved the bioavailability and kinetic profile of drugs in biological systems

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• ASA physical status I and II.

• Aged 3-7 yrs.

• Undergoing bone marrow aspiration and biopsy.

Exclusion Criteria:

• Allergy to the study drugs.

• Significant organ dysfunction.

• Cardiac dysrhythmia.

• Congenital heart disease.

• Use of psychotropic medication.

• Mental retardation.