Reactogenicity, Safety, and Immunogenicity of Covid-19 Vaccine Booster
Status:
Active, not recruiting
Trial end date:
2022-06-30
Target enrollment:
Participant gender:
Summary
Preliminary data suggest that inactivated vaccine-induced neutralizing antibodies against
SARS-CoV-2 decrease at six months after vaccination. Observational, unpublished data also
indicate that vaccine effectiveness against Covid-19 wanes over time. Thus, the investigators
aimed to determine the reactogenicity, safety, and immunogenicity of a homologous or
heterologous booster of SARS-CoV-2 vaccines among people already immunized with an
inactivated SARS-CoV-2 vaccine. The study focuses on the elderly population and healthcare
workers.
Phase:
Phase 2
Details
Lead Sponsor:
Universidad del Desarrollo
Collaborators:
Ministry of Health, Chile Pontificia Universidad Catolica de Chile University of Chile