Overview

Re-evaluation of the Effect Site Model of the PKPD Propofol Eleveld Model

Status:
RECRUITING
Trial end date:
2024-09-15
Target enrollment:
Participant gender:
Summary
in healthy patients undergoing elective surgery, after a very slow induction, using Eleveld's kinetics as a reference, after loss of consciousness (LOC) and intubation, proceed to infuse propofol until 1% burst suppression ratio is obtained. Then return to the LOC concentration. The BISindex predicted by the model and the real one will be evaluated. The evolution of spectral density frequencies over time will also be evaluated.
Phase:
PHASE4
Details
Lead Sponsor:
Universidad del Desarrollo
Collaborator:
Technical University of Munich