Re-entry XR-NTX for Rural Individuals With Opioid Use Disorder
Status:
Recruiting
Trial end date:
2022-03-31
Target enrollment:
Participant gender:
Summary
The overall aim of this R34 proposal is to examine the feasibility, acceptability, and
short-term outcomes associated with an innovative service delivery model to increase
adherence to extended-release naltrexone (XR-NTX) during the transition from jail to the
community for rural individuals with opioid use disorder (OUD). The significance of this
study is grounded in the public health emergency associated with the opioid epidemic in rural
Appalachia, the increased vulnerability of rural individuals with OUD, and the dearth of
available and accessible evidence-based treatment in the region. This study has potential to
make a significant contribution to the OUD treatment field by advancing knowledge on
innovative service delivery models to increase access to evidence-based treatment to reduce
the prevalence of opioid use disorders and related health disparities among hard-to-reach,
high-risk, underserved populations.