Rapid Effects of Hydrocortisone on Glucose-induced Insulin Secretion in Healthy Humans
Status:
Completed
Trial end date:
2008-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate the effect of hydrocortisone on glucose-induced
insulin secretion and sensitivity, by means of an intravenous glucose tolerance test with
frequent sampling (FSIGT) followed by minimal model analysis. In a randomized single-blind
cross-over design, the subjects will receive either hydrocortisone or placebo 4 minutes
before an intravenous glucose load.