Overview Rapid Antidepressant Effects of Leucine Status: Suspended Trial end date: 2022-06-30 Target enrollment: Participant gender: Summary This randomized double-blind placebo-controlled crossover study seeks to evaluate the antidepressant effect of L-leucine, an essential amino acid, in patients with Major Depressive Disorder (MDD). Phase: Phase 2 Details Lead Sponsor: University of Texas Southwestern Medical CenterTreatments: Antidepressive Agents