Overview

Rapamune Improves Outcomes of Severe H1N1 Pneumonia

Status:
Completed
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
Severe H1N1 pneumonia with acute respiratory failure shows hyperactive immune cells infiltration of lung. Rapamune, a mTOR inhibitor, modulates the immune response by blocking activation of T- and B-cells. To investigate the clinical efficiency of rapamune in severe H1N1 pneumonia with respiratory failure, this study was conducted.
Phase:
Phase 2
Details
Lead Sponsor:
Chang Gung Memorial Hospital
Treatments:
Everolimus
Sirolimus